In vivo Antimicrobial Activity Assessment of a Cauliflower By-Product Extract Against Salmonella Typhimurium

In vivo Antimicrobial Activity Assessment of a Cauliflower By-Product Extract Against Salmonella Typhimurium

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The main objective of this work was to study the antimicrobial effect of a cauliflower by-product infusion into an affordable in vivo model (Caenorhabditis elegans).The infusion demonstrated some protective effect on non-infected and infected worms with Salmonella Typhimurium as Book indicated by higher survival percentile values (75, 50, 25, and 5% percentiles) as compared with those from worms unexposed to the infusion.The antimicrobial effect of the infusion was evaluated on Salmonella intestinal colonization of infected worms (24, Custom Cushion 48, and 96 h post-infection).At 96 h post-infection, the concentration of Salmonella was reduced around 2 log cycles in infected cauliflower treated group (p < 0.

05) as compared with infected non-cauliflower group.Here we show that cauliflower by-products extend survival and have an antimicrobial effect in an in vivo nematode model, C.elegans, as a previous validation step to longer and costlier farm animal studies.